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由于在约旦的中混合病毒感染导致的呼吸系统疾病复杂
Mohammad Q Al-Natour1, Mohammed A Rohaim2, Rania F El Naggar3
1Division of Biomedical and Life Sciences, Faculty of Health and Medicine, Lancaster University, Lancaster LA1 4YG, United Kingdom; Department of Veterinary Pathology & Public Health, Faculty of Veterinary Medicine, Jordan University of Science and Technology (JUST), Irbid 22110, Jordan.
Poultry science
|February 28, 2024
概括
鸟类呼吸道病毒,包括传染性支气管炎病毒 (IBV) 和禽流感病毒 (AIV) H9N2,对约旦的家禽构成重大威胁. 这项研究分析了病毒菌株,揭示了突变和与区域病毒的遗传联系,强调需要加强监测和控制策略.
科学领域:
- 兽医病毒学 兽医病毒学
- 分子流行病学分子流行病学
- 禽类的健康 禽类的健康
背景情况:
- 鸟类呼吸道病毒需要强有力的监测和国际合作,以有效控制.
- 约旦的家禽业面临着呼吸道病毒感染带来的重大挑战.
研究的目的:
- 在约旦家禽中全面概述鸟类呼吸道病毒感染.
- 识别主要病毒,它们的流行病学,临床症状和遗传进化.
- 为改善诊断,控制策略和疫苗开发提供信息.
主要方法:
- 在 brojiler群中的呼吸道病毒病原体的分子分析 (2021年1月至2022年2月).
- 用RT-qPCR进行病毒身份验证.
- 针对IBV的全尖峰 (S1) 基因测序和针对AIV H9N2.2的血凝素 (HA) 基因测序.
- 遗传学分析和同时感染的检测.
主要成果:
- 死亡率在6%至40%之间.
- 检测到IBV和AIV H9N2的同时感染.
- IBV菌株属于GI-16和GI-23群体,具有多个突变.
- 艾滋病毒H9N2菌株显示HA基因变异,表明选择压力.
- 遗传学分析将H9N2病毒与EG3和中东 (ME1) 组联系起来.
结论:
- 鸟类呼吸道病毒感染是家禽部门的一个主要问题.
- 持续的警,改进的诊断,有效的疫苗和国际合作至关重要.
- 积极的措施是必不可少的,以尽量减少AI,IBV,ND和ILT病毒的影响.
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