相关实验视频
Updated: Jul 2, 2025
07:48
Working with Human Tissues for Translational Cancer Research
Published on: November 26, 2015
9.9K
改善英国公共研究机构临床试验透明度的障碍和最佳实践:一项定性访谈研究
Nicholas J DeVito1, Jessica Morley1, Ben Goldacre1
1Nuffield Department of Primary Care Health Science, University of Oxford, Oxford, United Kingdom.
Health policy (Amsterdam, Netherlands)
|February 28, 2024
概括
在政府施压后,英国公共研究机构制定了针对临床试验透明度的新政策. 虽然取得了进展,但在实现研究报告的全面透明度方面仍然存在挑战.
科学领域:
- 医疗保健服务研究 医疗服务研究
- 临床试验管理 临床试验管理
- 研究治理研究治理
背景情况:
- 自2017年以来,英国政府的举措强调从公共研究机构传播临床试验.
- 利益相关者的反应和内部政策的修改对于提高透明度至关重要.
研究的目的:
- 了解英国公共研究机构如何适应透明度压力.
- 确定最佳实践和提高临床试验透明度的障碍.
主要方法:
- 与来自英国公共机构的研究治理和试验管理人员进行半结构面试.
- 在采访数据的框架方法的帮助下进行主题分析.
主要成果:
- 新的政策和程序被广泛实施,以支持调查人员履行透明度承诺.
- 由于严格的法规,药品试验得到了最多的关注.
- 国家专业网络促进知识共享和最佳实践传播.
结论:
- 投资于机构透明度治理对于最佳实践至关重要.
- 大学和医院共同负责研究中的监管合规.
- 英国机构的努力为全球透明度倡议提供了洞察力.
相关概念视频
01:16Clinical Trials
6.7K
Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
There are four phases in a clinical trial. A phase one...
There are four phases in a clinical trial. A phase one...
6.7K
01:56Ethics in Research
23.0K
Today, scientists agree that good research is ethical in nature and is guided by a basic respect for human dignity and safety. However, this has not always been the case. Modern researchers must demonstrate that the research they perform is ethically sound.
23.0K
01:11Blinding
2.4K
Blinding is a commonly used method of not telling participants which treatment a subject is receiving. Blinding is a critical part of a randomized control trial or RCT. It reduces the bias that affects the results. In an RCT, blinding is used in the form of a placebo. A placebo effect occurs when untreated subjects falsely believe they have received the treatment and report improved symptoms. A placebo or a dummy treatment is administered to subjects to negate the bias caused by such an effect.
2.4K
01:23Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
126
Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
126
01:27Nursing Ethical Principles II
965
Ethical principles are essential in guiding nurses to fulfill their responsibilities, focusing on the quality of nursing care and decision-making. These principles, including autonomy, beneficence, non-maleficence, justice, and fidelity, shape the ethical framework within healthcare settings.
Consider the following scenario, which illustrates how these principles are applied in the care of Mr. John, a fifty-year-old teacher diagnosed with metastatic liver cancer.
Initially, Mr. John's...
Consider the following scenario, which illustrates how these principles are applied in the care of Mr. John, a fifty-year-old teacher diagnosed with metastatic liver cancer.
Initially, Mr. John's...
965
01:23Ethical Standards II
671
Ethical standards are the backbone of nursing practice, guiding nurses as they interact with patients, families, and colleagues. These standards are crucial for providing safe, empathetic care centered on the patient's needs.
Nurses are entrusted with upholding various ethical principles and standards. Nurses forge solid therapeutic relationships using trust, empathy, autonomy, confidentiality, and professional competence.
Confidentiality is crucial, embodying respect for individual privacy...
Nurses are entrusted with upholding various ethical principles and standards. Nurses forge solid therapeutic relationships using trust, empathy, autonomy, confidentiality, and professional competence.
Confidentiality is crucial, embodying respect for individual privacy...
671