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Updated: May 31, 2026

Standardized Colon Ascendens Stent Peritonitis in Rats - a Simple, Feasible Animal Model to Induce Septic Acute Kidney Injury
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开发一种可直肠注射的Dnase1,通过向NETs来治疗败血症休克

Su-Bin Kwak1, Sang-Jin Kim1, Yeon Jun Kang2

  • 1Department of Pharmacology, Seoul National University College of Medicine, Daehak-ro 103, Jongno-gu, Seoul 03080, Republic of Korea.

Life sciences
|February 28, 2024
PubMed
概括

通过直肠输送的工程脱氧核糖核酶 (AR-CR8) 通过降解中性粒细胞外细胞陷 (NETs) 来有效治疗败血症休克. 这种直肠提供了一个可行的替代方案,当静脉输入是不可能的紧急治疗.

关键词:
细胞透的.脱氧基核酶 1 1 脱氧基核酶中性细胞细胞外陷通过直肠给药.败血症的冲击是一个令人震惊的结果.

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Evaluation of a Reliable Biomarker in a Cecal Ligation and Puncture-Induced Mouse Model of Sepsis05:28

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