在9至11岁的早产儿中,出生体重,上腺,大脑形态测量和认知功能之间的关联
Weibin Ji1, Guanya Li1, Yang Hu1
1Center for Brain Imaging, School of Life Science and Technology, Xidian University and Engineering Research Center of Molecular and Neuro Imaging, Ministry of Education, Xi'an, Shaanxi, China; International Joint Research Center for Advanced Medical Imaging and Intelligent Diagnosis and Treatment and Xi'an Key Laboratory of Intelligent Sensing and Regulation of trans-Scale Life Information, School of Life Science and Technology, Xidian University, Xi'an, Shaanxi, China.
Biological psychiatry. Cognitive neuroscience and neuroimaging
|February 28, 2024
概括
过早出生婴儿的低出生体重与长期的认知和大脑发育问题有关,早期青春期开始起作用. 这项研究强调了未来干预的关键关联.
科学领域:
- 神经科学是一个神经科学.
- 发展生物学 发展生物学
- 儿科 儿科 儿科
背景情况:
- 过早出生和低出生体重增加持久神经和认知缺陷的风险.
- 与早产相关的内分泌和代谢变化可能会影响大脑发育.
- 关于出生体重,青春期和长期神经发育之间的相互作用的研究有限.
研究的目的:
- 研究出生体重与大脑结构,认知功能和青春期开始之间的关联.
- 为了检查这些关系在两个早产和满期的孩子.
主要方法:
- 在青少年大脑认知发展 (ABCD) 研究中利用了3571名儿童的数据.
- 评估出生体重,大脑形态测量,认知功能,以及上腺的发作 (青春期标志物).
- 分析是在出生后9至11年进行的.
主要成果:
- 在早产儿中观察到较低的出生体重和较早的上腺.
- 在所有儿童中,出生体重与认知功能和全球/区域大脑体积有正相关.
- 侧轨前皮层体积调解了低出生体重对早产儿认知的影响.
结论:
- 低出生体重显著影响长期的大脑结构和认知功能.
- 早期的上腺炎与这些影响有关,特别是在早产儿中.
- 研究结果为潜在的预防和治疗策略提供了见解.
相关概念视频
Biological Influences on Intelligence
100
Intelligence is often thought to be linked to brain size, but the relationship is more complex than that. While brain size does correlate modestly with some abilities, like verbal skills, the connection is weaker for others, such as spatial reasoning. Other factors, like brain structure, also play crucial roles. For instance, despite Einstein's smaller-than-average brain, his parietal cortex, which is involved in spatial reasoning, was 15% wider, suggesting that neural density might matter...
100
Attention-Deficit/Hyperactivity Disorder
67
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
67
Environmental Influences on Intelligence
288
Despite the strong genetic influence on traits like intelligence, environmental factors significantly shape outcomes. For example, while over 90% of height variation is due to genetic differences, environmental factors such as nutrition also have a notable impact. Similarly, for intelligence, changes in a child's surroundings can significantly alter their IQ. Research shows that enriched environments boost children's academic success and help them develop key cognitive skills. Children...
288
Information Processing Approach
37
The information-processing theory of cognitive development centers on fundamental mental processes, including attention, memory, and problem-solving skills. Researchers in this field examine how cognitive abilities, such as working memory, evolve and influence children's overall development. Studies indicate that children with stronger working memory tend to excel in reading comprehension, math, and problem-solving compared to peers with less efficient memory skills. Low working memory is...
37


