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通过纳入辅助效应的贝叶斯线性混合模型进行稳定性研究的现代方法

Miguel Cordero1, Florian Meinfelder1, Tobias Eilert2

  • 1Chair of Statistics and Econometrics, University of Bamberg, Feldkirchenstraße 21, D-96052 Bamberg.

Journal of pharmaceutical sciences
|February 28, 2024
PubMed
概括

本研究引入了使用线性混合模型 (LMM) 的贝叶斯方法,以改善药品保质期估计,解决目前ICH-Q1E稳定性测试和批量可变性指南中的局限性.

关键词:
辅助效应是一种辅助效应.批发批发的分发方式贝叶斯因子是一个贝叶斯因子.贝叶斯式借贷方式贝叶斯模型是贝叶斯模型.在ICH-Q1E.线性混合模型线性混合模型模型选择 模型选择保质期 货架上使用期限保质期的分配时间.稳定性研究研究.

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