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Updated: Jul 2, 2025

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全基因组增强剂相关的合重复在心肌病中得到扩展

Aleksandra Mitina1, Mahreen Khan2, Robert Lesurf1

  • 1Genetics and Genome Biology, The Hospital for Sick Children; Toronto, Ontario, Canada.

EBioMedicine
|February 28, 2024
PubMed
概括

罕见的双重重复扩张 (TREs) 与心肌病风险有关. 这些在一般人群中不常见的扩张,在接近开始地点的基因中发现,并可能减少基因表达,导致大约4%的心肌病病例.

关键词:
心肌病 (CMP) 是一种心肌病.长读序列的测序方式串联重复扩展 (TREs) 是一种重复扩展.转录条例 转录条例 转录条例 转录条例

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