饮食模式与与糖尿病相关的并发症的关联在糖尿病内型之间有所不同
Katharina S Weber1, Sabrina Schlesinger2, Alexander Lang2
1Institute of Epidemiology, Kiel University, Kiel, Germany.
Nutrition, metabolism, and cardiovascular diseases : NMCD
|February 28, 2024
概括
在新型糖尿病内型中,饮食模式的坚持略有变化,在hsCRP等并发症中发现了较小的关联. 目前的证据不足以为内型特异的饮食建议.
科学领域:
- 内分泌学和新陈代谢学
- 营养科学 营养科学
- 临床研究 临床研究
背景情况:
- 了解不同糖尿病内型的饮食模式的坚持对于个性化管理至关重要.
- 以前的研究还没有完全阐明这些差异及其对糖尿病并发症的影响.
研究的目的:
- 评估不同糖尿病内型的特定饮食模式 (地中海,DASH,植物性) 的遵守情况.
- 调查饮食坚持与心血管风险因素,功能和神经病变在这些内型之间的关联.
主要方法:
- 来自德国糖尿病研究的765名个体的横截面分析,分为五种内型:SAID,SIDD,SIRD,MOD和MARD.
- 使用食物频率问卷评估了饮食模式的坚持,计算了MDS,DASH,PDI,hPDI和UPDI的得分.
- 用多变量线性回归和通用混合模型来分析关联和差异.
主要成果:
- 轻度与年龄相关的糖尿病 (MARD) 显示出对健康植物性饮食指数 (hPDI) 的遵守率最高,而严重胰岛素缺乏糖尿病 (SIDD) 和轻度与肥胖相关的糖尿病 (MOD) 显示出最低.
- 在患有MARD的个体中,遵守几个饮食模式与高敏感性C反应蛋白 (hsCRP) 相反相关.
- 坚持植物性饮食指数与严重自身免疫性糖尿病 (SAID),严重胰岛素抵抗性糖尿病 (SIRD) 和MOD中的LDL胆固醇水平有关.
结论:
- 在糖尿病内型中,饮食模式坚持存在微小的变化,对于糖尿病相关并发症的标志物观察到一些关联.
- 目前的证据不足以确定糖尿病管理的内型特异性饮食建议.
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