相关实验视频

Updated: Jul 28, 2026

Osmotic Avoidance in Caenorhabditis elegans: Synaptic Function of Two Genes, Orthologues of Human NRXN1 and NLGN1, as Candidates for Autism
11:20

Osmotic Avoidance in Caenorhabditis elegans: Synaptic Function of Two Genes, Orthologues of Human NRXN1 and NLGN1, as Candidates for Autism

Published on: December 11, 2009

11.8K

在老鼠中,神经素1α的淘汰会导致异常的社会行为:对自闭症和精神分裂症的相关性

E J Marijke Achterberg1, Barbara Biemans2, Louk J M J Vanderschuren3

  • 1Department of Population Health Sciences, Section Animals in Science and Society, Faculty of Veterinary Medicine, Utrecht University, Utrecht, the Netherlands. e.j.m.achterberg@uu.nl.

Psychopharmacology
|February 28, 2024
PubMed
概括

在老鼠中,神经素1α基因被删除导致过度的社交游戏,游戏剥夺没有改变. 这表明了儿童精神障碍中无抑制的社会行为模式,与自闭症谱系障碍和精神分裂症社会退缩不同.

关键词:
自闭症 自闭症 自闭症在Neurexin1α的淘汰中,老鼠被淘汰了.精神分裂症是一种精神分裂症.社会行为社会行为.社会动机 社会动机社交游戏是一种社交游戏.

更多相关视频

Recording Mouse Ultrasonic Vocalizations to Evaluate Social Communication10:28

Recording Mouse Ultrasonic Vocalizations to Evaluate Social Communication

Published on: June 5, 2016

22.5K
Assessing Social Dominance in Mouse Models Using the Tube Test03:34

Assessing Social Dominance in Mouse Models Using the Tube Test

Published on: June 6, 2025

113

相关概念视频

Neural Regulation01:37

Neural Regulation

Digestion begins with a cephalic phase that prepares the digestive system to receive food. When our brain processes visual or olfactory information about food, it triggers impulses in the cranial nerves innervating the salivary glands and stomach to prepare for food.
Excitatory and Inhibitory Effects of Neurotransmitters01:29

Excitatory and Inhibitory Effects of Neurotransmitters

When an action potential reaches the presynaptic axon terminal, it releases neurotransmitters from the neuron into the synaptic cleft at a chemical synapse. The released neurotransmitter can be excitatory or inhibitory. The critical criteria commonly used to determine whether a molecule is a neurotransmitter at a chemical synapse are the molecule's presence in the presynaptic neuron. Second, its release is in response to strong presynaptic depolarization. And lastly, the presence of specific...
Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders01:27

Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders

Schizophrenia is a neurodevelopmental disorder whose origins are rooted in complex genetic components. Despite our burgeoning understanding, the pathophysiology of this disorder remains incompletely deciphered.
Researchers have identified genetic factors that increase susceptibility to schizophrenia, underscoring the intricate interplay between genetics and environment in disease development. At the core of schizophrenia's pathophysiology is excessive dopaminergic neurotransmission within the...
Biological Causes of Schizophrenia01:29

Biological Causes of Schizophrenia

Schizophrenia, a severe psychiatric disorder, arises from a complex interplay of biological factors, including genetic predisposition, structural brain abnormalities, neurotransmitter dysregulation, and developmental irregularities. These factors collectively contribute to the onset and progression of the disorder, which typically manifests in late adolescence or early adulthood.
Genetic Factors in Schizophrenia
The genetic basis of schizophrenia is strongly supported by family and twin studies.
Gut-Brain Axis01:22

Gut-Brain Axis

The gut–brain axis is a bidirectional communication system that connects the gastrointestinal tract and the brain. This interaction is mediated through multiple pathways, including the vagus nerve, hormonal signals, immune responses, and chemical messengers produced by gut microbes.Microbial Contributions to Brain FunctionGut microbiota contributes significantly to brain function by producing neuroactive compounds. These include neuroactive compounds that influence neurotransmitters such as...