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Updated: Jul 2, 2025

Tailoring In Vivo Cytotoxicity Assays to Study Immunodominance in Tumor-specific CD8+ T Cell Responses
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抗TIGIT抗体通过骨髓和Treg细胞改善PD-L1阻塞

Xiangnan Guan1, Ruozhen Hu1, Yoonha Choi1

  • 1Genentech Inc., South San Francisco, CA, USA.

Nature
|February 28, 2024
PubMed
概括

通过激活免疫细胞,提拉古卢马布与阿特佐利祖马布结合改善癌症的结果. 这种免疫疗法组合增强了巨细胞和T细胞的反应,表明TIGIT抑制剂的新机制.

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相关概念视频

Tumor Immunotherapy01:27

Tumor Immunotherapy

Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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