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Updated: Jul 2, 2025

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释放肝细胞癌的攻击性:通过STAMBPL1介导的TRAF2二维基化激活了WNT/PI3K/NF-kb信号通路

Zhihuai Wang1,2, Yinjie Zhang1,2, Yuhang Shen1,2

  • 1Nanjing Medical University, Nanjing, 211166, China.

Biology direct
|February 28, 2024
PubMed
概括

通过稳定TRAF2,激活关键癌症通路,STAMBPL1二维基因酶活性促进肝细胞癌 (HCC). 这一发现突出了STAMBPL1作为HCC的潜在生物标志物和治疗目标.

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