发育中的人类胎儿阴茎和阴蒂的神经血管解剖学
Sena Aksel1, Amber Derpinghaus1, Mei Cao1
1Department of Urology, University of California, San Francisco, California, USA.
Journal of anatomy
|February 28, 2024
概括
这项研究揭示了使用先进显微镜开发人类阴茎和阴蒂的独特的神经血管解剖学. 研究人员发现了一种新奇的东西.
科学领域:
- 发展生物学 发展生物学
- 人类解剖学 人类解剖学
- 神经科学是一个神经科学.
背景情况:
- 人类的阴茎和阴蒂发育源于一个共同的生殖器结核.
- 雄激素的影响决定了阴茎 (带尿道) 或阴蒂 (没有尿道) 的分化.
- 形态差异源于发育过程中复杂的道化.
研究的目的:
- 定义正在发育的阴茎和阴蒂的血管和神经解剖学.
- 为了研究妊娠8至12周之间的解剖学差异.
- 使用激光扫描共聚焦显微镜进行详细分析.
主要方法:
- 激光扫描共聚焦显微镜.
- 对CD31 (内皮细胞标记物) 和PGP9.5 (神经元标记物) 的免疫组合化学联合表达分析.
- 在怀孕8至12周之间检查胎儿样本.
主要成果:
- 在正在发育的阴茎腹腔轴中表明CD31和PGP9.5的共同表达.
- 确定了一种新的胎儿结构,即"阴蒂脊",沿着阴蒂轴.
- 揭示了成长中的阴茎和阴蒂之间的细微神经血管解剖差异.
结论:
- 胎儿发育导致阴茎和阴茎的不同神经血管解剖学.
- "阴蒂脊"是一个新发现的解剖结构.
- 先进的显微镜突出了微妙但重要的解剖学差异.
更多相关视频
04:08Author Spotlight: Optimizing the Neurovascular Development of Human Brain Organoid in Chick Embryo
Published on: February 16, 2024
1.5K
10:28Assessment of Ultrastructural Neuroplasticity Parameters After In Utero Transduction of the Developing Mouse Brain and Spinal Cord
Published on: February 26, 2019
6.9K
相关概念视频
Penis
4.6K
The penis serves a dual role in sexual reproduction and urination. It consists of three main regions: the glans penis, the body, and the root, each with distinct functions and unique anatomical features.
Anatomy of the Penis
The glans penis, or the head, is the terminal part of the penis and houses the external urethral orifice, the exit point for urine and semen. Covered by the prepuce, or foreskin, the glans is noted for its sensitivity and plays a key role in sexual pleasure. The body of the...
Anatomy of the Penis
The glans penis, or the head, is the terminal part of the penis and houses the external urethral orifice, the exit point for urine and semen. Covered by the prepuce, or foreskin, the glans is noted for its sensitivity and plays a key role in sexual pleasure. The body of the...
4.6K
Development of the Sexual Organs in the Embryo and Fetus
704
Development of the reproductive organs in an embryo starts from a bipotential state. This means the early embryo can develop either male or female reproductive organs. The formation of these organs begins with the growth of gonadal ridges that arise from the intermediate mesoderm during the fifth week of development.
Near the gonadal ridges, two duct systems are present: the mesonephric ducts (Wolffian ducts) and paramesonephric ducts (Müllerian ducts). These ducts form the basis for the...
Near the gonadal ridges, two duct systems are present: the mesonephric ducts (Wolffian ducts) and paramesonephric ducts (Müllerian ducts). These ducts form the basis for the...
704
External Female Genitals
6.3K
The vulva encompasses the external structures of the female reproductive system. At the forefront is the monpubis, a cushion of fatty tissue atop the pubic bone. Once puberty sets in, this area typically grows hair. Extending from just behind the mons pubis are the labia majora (labia = 'lips'; majora = 'larger'), which are larger skin fs olds coated with hair. Nestled within are the labia minora (labia = 'lips'; minora = 'smaller'), which are thinner, more...
6.3K
Neurulation
41.9K
Neurulation is the embryological process which forms the precursors of the central nervous system and occurs after gastrulation has established the three primary cell layers of the embryo: ectoderm, mesoderm, and endoderm. In humans, the majority of this system is formed via primary neurulation, in which the central portion of the ectoderm—originally appearing as a flat sheet of cells—folds upwards and inwards, sealing off to form a hollow neural tube. As development proceeds, the...
41.9K
Development of Blood Vessels
583
The development of the vascular system in a fetus is a complex and intricate process that begins as early as 15 to 16 days post-conception. This process starts outside the embryo, specifically in the mesoderm of the yolk sac, chorion, and connecting stalk. Approximately two days later, the formation of blood vessels occurs within the embryo itself.
The initial formation of this system is facilitated by the small amount of yolk present in the ovum and yolk sac. Blood vessels originate from...
The initial formation of this system is facilitated by the small amount of yolk present in the ovum and yolk sac. Blood vessels originate from...
583
The Spinal Cord
29.3K
The spinal cord is the body’s major nerve tract of the central nervous system, communicating afferent sensory information from the periphery to the brain and efferent motor information from the brain to the body. The human spinal cord extends from the hole at the base of the skull, or foramen magnum, to the level of the first or second lumbar vertebra.
29.3K
