在COVID期间抗抗菌素抗抗菌素的增加:非理性利用的作用
Sidra Tanwir1, Arif Sabah1, Ambrina Khatoon1
1Ziauddin University, Karachi, Pakistan.
JPMA. The Journal of the Pakistan Medical Association
|February 29, 2024
概括
在COVID-19期间,阿齐思罗米的使用增加导致了更高的抗菌素耐药性. 对肺炎和伤寒等疾病的不合理处方导致了城市环境中的这一令人担忧的趋势.
科学领域:
- 药理学 药理学是指药理学的学科.
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 冠状病毒疾病-2019 (COVID-19) 流行病导致了广泛使用抗生素,包括阿兹特罗米.
- 人们担心抗生素消费增加对抗菌素耐药性 (AMR) 的影响.
研究的目的:
- 为了评估在COVID-19大流行期间的阿齐思罗米利用情况.
- 评估这种使用对城市人口抗菌素耐药性的影响.
主要方法:
- 一项回顾性,横截面研究分析了两个数据集:COVID-19第一波的住院患者数据 (N=300) 和2019-2021年的药房消费/抗生素数据.
- 对药物使用的评估是根据COVID-19和巴基斯坦医学微生物学和传染病学会 (MMIDSP) 的指导方针进行评估的.
- 用SPSS 20进行数据分析.
主要成果:
- 在实验中,阿齐思罗米被规定给所有300名住院患者,只有21%的病例进行了培养敏感性测试.
- 虽然遵守COVID-19协议的程度很高 (97%),但在社区获得的肺炎 (95%),伤寒 (75%) 和尿路炎 (100%) 方面观察到严重的不遵守MMIDSP指南.
- 抗生素检查数据显示,对亚齐菌素的耐药性增加.
结论:
- 在COVID-19大流行期间,阿齐思罗米的增加消费和不合理使用与抗菌素耐药性的增加密切相关.
- 这强调了需要合理的抗生素处方来缓解AMR的发展.
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