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Updated: Jul 2, 2025

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CK1ε/SIAH1轴调节了结直肠癌细胞中的AXIN1稳定性

Mengfang Yan1,2, Zijie Su1,3, Xiaoyi Pang1

  • 1Guangdong Provincial Key Laboratory of Regional Immunity and Disease, International Cancer Center, Marshall Laboratory of Biomedical Engineering, Department of Pharmacology, Shenzhen University Medical School, Shenzhen University, China.

Molecular oncology
|February 29, 2024
PubMed
概括

素激酶1ε (CK1ε) 针对轴抑制剂1 (AXIN1) 的降解,促进结直肠癌 (CRC) 的生长. 抑制CK1ε稳定了AXIN1,抑制了CRC的进展,并提供了一个新的治疗策略.

关键词:
在AXIN1中,AXIN1是AXIN1的前身.在CK1ε.一个SIAH1公司.在Wnt/β-catenin中使用.结肠直肠癌是什么意思无处不在的化

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