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Updated: Jul 2, 2025

Facile Preparation of 4-Substituted Quinazoline Derivatives
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Published on: February 15, 2016

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探索新的quinazolin-4(3H) -one衍生物作为CDK2抑制剂:设计,合成和抗癌评估

Basant T Ibrahim1, Heba Abdelrasheed Allam2, Nehad M El-Dydamony1

  • 1Pharmaceutical Chemistry Department, College of Pharmaceutical Sciences and Drug Manufacturing, Misr University for Science and Technology, 6th of October City, Egypt.

Drug development research
|February 29, 2024
PubMed
概括

新的quinazolinone衍生物通过抑制循环素依赖性激酶2 (CDK2) 来表现出强大的抗癌活性. 这些化合物有效地诱导中枢神经系统,黑色素瘤和肺癌细胞系中的细胞死亡,提供了有前途的药物开发支架.

关键词:
这是一种CDK2抑制剂.它具有抗癌活性,具有抗癌活性.化皮里米丁化皮里米丁.这是一种quinazolineine.

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