前列腺活检可能不适用于Bacillus Calmette Guérin治疗后的早期治疗
Naoki Akagi1, Akihiro Kanematsu1, Koji Shigesaka1
1Department of Urology, Hyogo Medical University.
Acta medica Okayama
|February 29, 2024
概括
在治疗膀癌后一年内进行前列腺活检 (Bacillus Calmette-Guérin (BCG)) 并没有信息. 早期活检显示癌症检测率较低,这表明延迟评估对于检测前列腺癌更有用.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 在瘤学瘤学.
- 病理学 病理学 病理学
背景情况:
- 巴西勒斯卡尔梅特-盖林 (BCG) 免疫疗法是治疗非肌肉侵入性膀癌的标准治疗方法.
- 乳腺内BCG颗粒瘤的形成是BCG治疗后的常见并发症.
- 在BCG治疗后进行前列腺活检的最佳时间尚不清楚.
研究的目的:
- 在非肌肉侵入性膀癌患者接受BCG治疗后,研究前列腺活检的诊断产量和最佳时间.
- 评估活检时间,前列腺特异性抗原 (PSA) 水平,MRI发现和前列腺癌检测率之间的关系.
主要方法:
- 在BCG治疗后接受前列腺活检的22名患者的回顾性分析 (2013-2017年).
- 活检是指PSA升高,异常的数字直肠检查或MRI发现.
- 与28名不接受BCG治疗的年龄和PSA匹配患者的对照组进行比较.
主要成果:
- 前列腺癌仅在BCG组的13.9%患者中检测到,而对照组的78.5% (p=0.0001).
- 在BCG组中,所有三个前列腺癌诊断都发生在治疗后一年以上.
- 在BCG治疗后一年内进行的活检没有产生癌症诊断.
结论:
- 在BCG治疗非肌肉侵入性膀癌后一年内进行的前列腺活检具有较低的诊断产量.
- 延迟前列腺活检,通常是BCG治疗后1年,可能更有信息来检测前列腺癌.
- 当前的指导方针可能需要对BCG治疗的患者前列腺活检的时间进行修订.
关键词:
菌 Calmette-Guérin-Guérin-Guérin-Calmette-Guérin-Guérin-Guérin,也就是卡尔梅特 - 格瑞恩菌的意思,就是说,它是一种细菌.膀癌:膀癌是一种癌症.前列腺活检 活检前列腺活检前列腺癌是前列腺癌.前列腺小粒瘤前列腺小粒瘤更多相关视频
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