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老年人与无声大脑小血管疾病的手写运动异常 - 一项初步研究

Hongyi Zhao^1,2, Liyi Chi³, Hans-Leo Teulings⁴

¹Department of Neurology, Seventh Medical Centre of Chinese PLA General Hospital, 100700 Beijing, China.

Journal of integrative neuroscience

|February 29, 2024

概括

患有脑小血管疾病 (CSVD) 的老年人表现出异常的手写. 数字化分析揭示了与CSVD严重程度相关的运动变化,为神经影响提供了洞察力.

科学领域:

神经学神经学
生物医学工程生物医学工程
老年病的医生老年病的医生

背景情况:

大脑小血管疾病 (CSVD) 呈现出一系列症状,从无症状的放射学发现到显著的认知和运动障碍.
手写和步态下降是认可的CSVD的临床表现.
数字化手写动态评估提供了一种新的方法,可以客观地评估微妙的运动变化.

研究的目的:

为了调查CSVD的老年人是否表现出异常的手写运动.
评估数字化手写分析在检测和量化这些异常的有用性.
探索手写动力学参数与CSVD严重程度之间的相关性.

主要方法:

60名老年人根据Fazekas分数被分为严重的CSVD,非严重的CSVD和健康组.
在签名写作,汉字转录和阿基米德的螺旋绘图任务中收集了运动数据.
分析的重点是诸如速度,扭曲度,尺寸和手写和绘图任务中的冲动等参数.

主要成果:

与其他组相比,严重的CSVD组在签名写作中表现出降低的速度和增加的扭曲性.
在严重的CSVD组中观察到中风速度和字符大小的异常.
两组CSVD均表现出高于健康组的平均正常化抽,与CSVD负担相关.

结论:

患有CSVD的老年人表现出明显的手写运动异常.
数字化的手写分析有效地捕捉到这些异常.
手写障碍的程度与大脑小血管疾病的严重程度相关.

关键词:

老化的老化衰老的老化大脑小血管疾病是大脑小血管疾病.分析手写的分析.动力学是动力学.磁共振成像 (MRI) 的使用.白质的超强度是白质的超强度.

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