在接受内巴克洛芬试验的儿童中,打开压力和腰椎穿刺后头痛
Amanda E Summers1, Jenny L Wilson1,2
1Department of Pediatric Neurology, Oregon Health & Science University, Portland, OR, USA.
Journal of child neurology
|February 29, 2024
概括
腰部刺穿后头痛发生在接受内巴克洛芬试验的儿童中的16.3%. 升高的开口压力是关键预测因素,建议在这些头痛的风险评估中使用它.
科学领域:
- 儿科神经学 儿科神经学
- 神经外科 神经外科
背景情况:
- 腰部刺痛后头痛 (PLPH) 是一种已知的并发症,影响5-12%的儿科患者.
- 患有高血压的儿童在诊断或治疗腰部刺穿期间可能具有独特的PLPH风险因素.
研究的目的:
- 为了确定PLPH的频率和预测因子,在患有高血压的儿科患者进行椎穿刺,进行内巴克洛芬试验.
- 在这个特定的人群中评估开口压力和PLPH之间的关系.
主要方法:
- 对43名患有高血压/运动障碍的儿科患者 (<18岁) 进行了回顾性单一中心审查,这些患者正在接受内巴克洛芬试验 (2013-2022).
- 使用双向配对t测试和费舍尔精确测试来评估PLPH的预测因素的统计分析.
- 分析了打开压力测量与PLPH发病率的相关性.
主要成果:
- 七名受试者 (16.3%) 患有PLPH;3人需要紧急护理/住院治疗.
- 与没有PLPH (22.4厘米H2O,P=.014) 的患者相比,PLPH患者的平均开口压力明显高 (28.6厘米H2O).
- 60%的患有高开口压力 (>28厘米H2O) 的患者患有PLPH;在大多数情况下,巴克洛芬安置没有并发症.
结论:
- 该队列中PLPH的发病率高于之前报告的,可能是由于升高开口压力的更高患病率.
- 开口压力测量可以帮助预测在儿童进行内巴克洛芬试验的PLPH风险.
- 升高的开口压力或PLPH并不一定是对内巴克洛芬放置的禁忌.
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