年轻人的易怒:一个批判性的综合性审查
Ellen Leibenluft1, Laura E Allen1, Robert R Althoff1
1Emotion and Development Branch, NIMH, Bethesda, Md. (Leibenluft, Brotman, Kircanski, Malone, Pine); Faculty of Brain Sciences, Division of Psychiatry and Division of Psychology and Language Sciences, University College London (Allen, Stringaris); Departments of Psychiatry, Pediatrics, and Psychological Science, University of Vermont, Burlington (Althoff); Department of Psychological Sciences, University of Connecticut, Storrs (Burke); Division of Child and Adolescent Psychiatry, Department of Psychiatry (Carlson), Department of Psychology (Klein, Silver), and Department of Psychiatry (Klein), Stony Brook University, Stony Brook, N.Y.; Division of Child and Adolescent Psychiatry, McLean Hospital, Harvard Medical School, Belmont, Mass. (Dickstein); Department of Psychology, University of Maryland, College Park (Dougherty); Department of Psychology, University of Miami, Coral Gables, Fla. (Evans); Departments of Psychiatry, Psychology, and Clinical and Translational Science, University of Pittsburgh, Pittsburgh (Mazefsky); Department of Psychiatry, Oregon Health and Science University, Portland (Nigg); Department of Psychology, Washington University at St. Louis, St. Louis (Perlman); Department of Psychology, Fordham University, New York (Roy); Child Mind Institute, New York (Salum); Division of Psychological Medicine and Clinical Neurosciences, Wolfson Centre for Young People's Mental Health, Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, Wales, United Kingdom (Shakeshaft, Thapar); Division of Child and Adolescent Mental Health, Children's Hospital Colorado, University of Colorado School of Medicine, Denver (Stoddard); Yale Child Study Center, Yale School of Medicine, New Haven, Conn. (Tseng); Child and Adolescent Mental Health Research Group, Institut de Recerca Sant Joan de Déu, Esplugues de Llobregat, Barcelona, Spain (Vidal-Ribas); Department of Medical Social Sciences, Institute for Innovations in Developmental Sciences, and Institute for Policy Research, Northwestern University, Chicago (Wakschlag); First Department of Psychiatry, National and Kapodistrian University of Athens, and Aiginiteion Hospital, Athens, Greece (Stringaris).
年轻人易怒,这是一个常见的问题,与严重的损伤和未来的心理健康风险有关. 研究强调了它的发展途径,遗传联系,以及需要更好的评估和有针对性的干预措施.
科学领域:
- 儿童和青少年精神病学
- 发展心理学 发展心理学
- 行为神经科学 行为神经科学
背景情况:
- 易怒是年轻人普遍存在的疾病,其特点是容易生气,这可能会损害功能.
- 最近的研究激增,需要整合当前的临床和翻译发现.
- 现有的评估工具可用,但告知效应 (根据谁报告症状的变化) 是显著的,需要仔细考虑.
研究的目的:
- 系统地审查和整合关于青少年易怒性的最新临床和翻译研究.
- 确定研究缺口,并为未来的研究方向提供建议.
- 讨论评估,发育轨迹,遗传基础和年轻人易怒的治疗.
主要方法:
- 综合系统和叙事审查方法.
- 临床和翻译研究结果的整合.
- 对发育轨迹,遗传关联和治疗疗效的分析.
主要成果:
- 在患有注意力缺陷多动症,自闭症谱系障碍和情绪/焦虑障碍的年轻人中,易怒性非常普遍.
- 易怒与功能障碍和自杀风险增加有关,独立于其他诊断.
- 易怒的发育轨迹是可以识别的,从生命早期开始,并预测以后的不良结果,包括焦虑,抑郁,行为问题和自杀倾向.
结论:
- 建议对年轻人的易怒性进行常规评估,使用现有的工具,同时承认告知者效应.
- 对丧和威胁的异常反应是刺激性病理生理学的核心,提供了翻译性研究机会.
- 需要对大型,多样化的纵向样本,文化背景和刺激性机制的干预措施进行进一步的研究.
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