阻塞性睡眠呼吸暂停和心房动的性别差异:心房动负担的影响
Chou-Han Lin1, Yen-Bin Liu2, Lian-Yu Lin2,3
1Division of Respiratory Medicine, Department of Internal Medicine, Far Eastern Memorial Hospital, New Taipei City, Taiwan.
International journal of cardiology. Heart & vasculature
|February 29, 2024
概括
心房的负担是阻塞性睡眠呼吸暂停的危险因素,但仅在男性中. 患有这两种疾病的女性,尽管年龄较大,但心房的负担较低.
科学领域:
- 心脏病学 心脏病学
- 睡眠医学 睡眠医学
- 内部医学 内部医学
背景情况:
- 阻塞性睡眠呼吸暂停 (OSA) 是心房动 (AF) 的已知危险因素.
- 在患有AF和OSA的患者中,相互关系和性别特异性差异尚不清楚.
研究的目的:
- 为了确定是否增加心房的负担与OSA相关.
- 研究患有AF和OSA的患者临床特征的性别差异.
主要方法:
- 一项前性队列研究的描述性,横截面分析.
- 患有非膜性AF的患者接受了家庭睡眠呼吸暂停测试和14天心电图监测.
- 中度至重度的OSA被定义为呼吸暂停-呼吸暂停指数≥15.5.
主要成果:
- 超过一半 (53.4%) 的AF患者有中度至重度的OSA.
- 男性比女性 (38.2%) 更有可能患有中度至重度的OSA (59.3%).
- AF负担仅在男性中与中度至重度的OSA相关;患有OSA的女性年龄较大,但BMI和OSA严重程度相似,但AF负担较低.
结论:
- 心房的负担是OSA的性别特异性风险因素,仅在男性中观察到.
- 与男性相比,患有同时存在的AF和OSA的女性的AF负担较低,尽管OSA的严重程度和体重指数相似.
- 这些发现表明,AF可能在患有OSA的女性中比男性晚发展.
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