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Updated: Jul 2, 2025

Sequence-specific and Selective Recognition of Double-stranded RNAs over Single-stranded RNAs by Chemically Modified Peptide Nucleic Acids
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反感性寡核酸的组织药理学

Erica Bäckström1, Alessandro Bonetti2, Per Johnsson2

  • 1Drug Metabolism and Pharmacokinetics, Research and Early Development, Respiratory & Immunology (R&I), BioPharmaceuticals R&D, AstraZeneca, 431 83 Gothenburg, Sweden.

Molecular therapy. Nucleic acids
|February 29, 2024
PubMed
概括

反感性寡核酸 (ASOs) 呈现出快速的组织分布和缓慢的消除. 这项研究量化了ASO的药理动力学和RNA在组织,途径和化学物质中的敲除,有助于药物发现.

关键词:
MT:寡核酸:疗法和应用.反感的寡核化物.分销 销售 分销 销售 分销 销售剂量与剂量成比例.这里是鼠标鼠标鼠标鼠标鼠标鼠标.药物动力学 药物动力学组织组织组织组织组织.

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