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接种HIV-1疫苗后的先天性免疫细胞激活与抗体生产增加有关

Kombo F N'guessan1,2, Kawthar Machmach1,2, Isabella Swafford1,2

  • 1United States Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, United States.

Frontiers in immunology
|February 29, 2024
PubMed
概括

这项关于RV306艾滋病毒疫苗试验的研究发现,在接种疫苗后,NK,MAIT和γδ T细胞等先天性免疫细胞会被激活. 这种激活与抗体反应有关,这表明这些细胞在促进疫苗诱导的免疫力方面发挥了作用.

关键词:
艾滋病毒疫苗 艾滋病毒疫苗MAIT (粘膜相关的不变T) 细胞.在 NK 细胞中, NK 细胞是最重要的.玛三角形 (γδ) T细胞 T细胞在iNKT细胞中.免疫激活系统的激活单细胞 (Monocytes) 是一种单细胞.

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