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Updated: Jul 2, 2025

Preparation of Acute Hippocampal Slices from Rats and Transgenic Mice for the Study of Synaptic Alterations during Aging and Amyloid Pathology
14:57

Preparation of Acute Hippocampal Slices from Rats and Transgenic Mice for the Study of Synaptic Alterations during Aging and Amyloid Pathology

Published on: March 23, 2011

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通过HDAC9介导的卡尔莫杜林脱乙化诱导阿尔茨海默氏病的记忆障碍

Hai-Long Zhang1, Shufen Hu1, Pin Yang2

  • 1Jiangsu Key Laboratory of Neuropsychiatric Diseases, Institute of Neuroscience, Suzhou Medical College of Soochow University, Medical Center of Soochow University, Suzhou, China.

CNS neuroscience & therapeutics
|February 29, 2024
PubMed
概括

减少calmodulin (CaM) 乙化,由HDAC9驱动,在阿尔茨海默病 (AD) 中损害记忆力. 向HDAC9或增强CaM乙化可能为AD提供新的治疗策略.

关键词:
阿尔茨海默病的疾病阿尔茨海默病的疾病.在 CaM CaM 中.在HDAC9的基础上.乙化处理的方法记忆障碍 记忆障碍 记忆障碍

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