在重症患者中实施疼痛,兴奋,妄想和睡眠剥夺协议:关于药理干预的试点研究
Punchika Luetrakool1, Suthinee Taesotikul2, Kanyarat Susantitapong3,4
1Department of Anesthesiology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Clinical and translational science
|February 29, 2024
概括
疼痛,兴奋,妄想和睡眠剥夺 (PADS) 协议改善了重症患者的治疗结果. 实施导致了更多的无ICU日,以及更少的妄想和二使用.
科学领域:
- 关键护理医学 关键护理医学
- 重症监护病房管理部门的管理.
- 患者研究成果研究结果
背景情况:
- 危急病患者经常遭受疼痛,动荡,妄想和睡眠剥夺.
- 这些症状与增加的死亡率和不良的临床结果有关.
- 疼痛,兴奋,妄想和睡眠不足 (PADS) 协议是为了解决这些问题而开发的.
研究的目的:
- 评估PADS协议对重症监护病房 (ICU) 临床结果的影响.
- 为了比较PADS协议实施之前和之后的患者结果.
主要方法:
- 在医疗和手术ICU中采用了前后研究设计.
- 分析了两个队列:协议前的254名患者 (2018年5月至2019年9月) 和之后的255名患者 (2020年5月至9月).
- 追溯和前性数据收集被用来比较结果.
主要成果:
- "之后"组显示14天无ICU日的显著增加 (9.95 vs 10.40天,p=0.014).
- 在"之后"组中, Delirium 发病率显著下降 (18.1%与16.1%,p<0.001).
- 在"后"组中,二胺使用量显著减少 (38.6%对24.6%,p=0.001).
结论:
- 该PADS协议显示了改善ICU患者护理的潜力.
- 实施PADS协议与更好的临床结果有关,包括减少妄想和药物使用.
- 该研究强调了PADS协议在加强重症监护管理方面的重要性.
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