德克萨斯州持续的贫困和基于发病率的黑色素瘤死亡率
Karla Madrigal1, Lillian Morris1, Kehe Zhang2,3
1John P. and Kathrine G. McGovern Medical School, The University of Texas Health Science Center, Houston, TX, USA.
Cancer causes & control : CCC
|February 29, 2024
概括
持续贫困 (PP) 县的黑色素瘤患者的死亡率更高. 解决这些地区的社会经济因素对于改善黑色素瘤结果和早期诊断至关重要.
科学领域:
- 在瘤学瘤学.
- 公共卫生 公共卫生
- 健康的社会经济决定因素
背景情况:
- 持续的贫困 (PP) 与较差的癌症结局有关.
- 对于PP对黑色素瘤结局的影响尚不清楚.
- 在PP区域的黑色素瘤患者可能面临独特的挑战.
研究的目的:
- 调查持续的贫困 (PP) 和基于黑色素瘤发病率的死亡率 (IMM) 之间的联系.
- 为了测试假设,PP县的黑色素瘤患者有更高的IMM率.
- 为高风险人群提供有针对性的干预信息.
主要方法:
- 利用了德克萨斯州癌症登记处 (2000-2018) 对82,458名黑色素瘤患者的数据.
- 将患者的居住区分为持续贫困 (PP) 或非持续贫困 (nPP) 县.
- 调整以人口学变量为准的使用后勤回归分析.
主要成果:
- 与nPP县 (11.3%) 相比,PP县的黑色素瘤患者的IMM显着更高 (17.4%).
- 调整后的赔率比为1.35 (95% CI 1.25-1.47),表明PP地区死亡风险增加.
- 在控制人口因素后,统计学意义保持不变.
结论:
- 持续的贫困是黑色素瘤特异性死亡率的重要风险因素.
- 在PP县的黑色素瘤患者的死亡率不成比例地高.
- 考虑到社会经济地位的基于地点的干预措施对于改善黑色素瘤护理和结果至关重要.
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