使用基于加多的对比剂的光谱计算机断层扫描血管学,用于对大动脉病理的成像
Markus Graf1, Felix G Gassert2, Alexander W Marka2
1Department of Diagnostic and Interventional Radiology, School of Medicine & Klinikum rechts der Isar, Technical University of Munich, Ismaninger Straße 22, 81675, Munich, Germany. markus.m.graf@tum.de.
基于加多的对比剂为患有大动脉动脉瘤的患者提供了可行的计算机断层扫描血管造影 (CTA) 的替代方案,这些患者不能使用基于的剂. 带有单能重建的光谱CT在这些情况下提供了可靠的大动脉成像.
科学领域:
- 放射学 放射学是一门学科.
- 医疗成像医学成像
- 心血管成像 - 心血管成像
背景情况:
- 患有大动脉动脉瘤的患者通常需要多个CTA.
- 基于的对比剂可能因医疗状况而被禁用.
- 基于加多的对比剂 (Gd-CTA) 是一个潜在的替代品.
研究的目的:
- 评估使用基于加多的对比剂进行光谱计算机断层扫描血管造影 (CTA) 的可行性.
- 评估它在患有大动脉动脉瘤的患者中具有对基对比剂的禁忌的有用性.
主要方法:
- 对15名患有大动脉动脉瘤的患者 (21次扫描) 进行了光谱CT.
- 患者对基对比剂有禁忌.患者对基对比剂有禁忌.
- 基于Gd的对比剂是以常规剂量 (0.2 mmol/kg) 给药的.
- 从光谱数据计算出单能重建.
主要成果:
- 用Gd-CTA显著增加血管内大动脉衰减 (p < 0.001).
- 与传统成像相比,单能重建 (MonoE40) 的对比率明显更高.
- 胸前动脉:6.5±4.5 (MonoE40) 与2.4±0.5 (传统) 相比,p=0.003.
- 腹腔大动脉:4.1±1.8 (MonoE40) 与1.9±0.5 (传统) 相比,p < 0.001.
结论:
- Gd-CTA是用于诊断大动脉成像的有效和可靠的替代方案.
- 使用Gd-CTA的单能重建对于患有大动脉动脉瘤和禁忌的患者是有用的.
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