在社区居住的老年人中,肥胖标志物和骨参数之间的关系
L Lemoine1,2, F Buckinx3,4, A Aidoud5,6
1Division of Geriatric Medicine, Tours University Medical Centre, Tours, France. lea.lemoine@univ-tours.fr.
Aging clinical and experimental research
|February 29, 2024
概括
肥胖与较高的骨密度有关,但不是皮质骨密度,在老年人中. 在肥胖个体中评估皮质骨密度可能有助于识别骨变化.
科学领域:
- 老年学是一门学科.
- 骨的新陈代谢 骨的新陈代谢
- 肥胖问题研究研究
背景情况:
- 骨质疏松症是一种与年龄相关的疾病,具有重大健康后果.
- 关于肥胖对骨健康的影响存在矛盾的文献,可能是由于各种肥胖指标和代谢因素.
- 体重指数 (BMI) 可能是肥胖的一个不完美的标志物,需要探索其他标准.
研究的目的:
- 研究骨变量与三个不同的肥胖标准之间的关系:BMI,腰围 (WC) 和脂肪质量 (FM).
- 为了澄清肥胖和老年人骨健康之间的复杂相互作用.
主要方法:
- 一项涉及168名55岁及以上成年人的横截面研究.
- 参与者根据BMI,WC和FM被归类为肥胖.
- 用双能X射线吸收度和外围定量计算断层扫描来评估骨变量和结构.
主要成果:
- 观察到肥胖的高患病率:BMI为28%,FM为64%,WC为87%.
- 骨变量与WC和BMI正相关 (r = 0.20.42).
- 在男性中,肥胖度与皮质骨密度 (r = -0.32~ -0.19) 有负相关,与皮质骨面积 (r = 0.220.39) 有正相关.
结论:
- 无论标准如何,肥胖通常与较高的骨参数相关,除皮层骨密度外.
- 对肥胖个体进行皮质骨密度评估可能有助于识别骨变化.
- 建议进行进一步的研究,以验证这些关于肥胖和骨健康的发现.
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