80年代以后的氧气吸收峰值作为生存预测指标
Fabricio Braga1,2, Mauricio Milani3,4,5, Ana Fachetti6,7
1Laboratório de Performance Humana, Largo do Ibam, no1-2o floor-Humaitá, Rio de Janeiro, RJ, 22271-070, Brazil. fabricio.braga@lphoficial.com.
氧气吸收峰值 (VO2峰值) 预测了八十岁人的生存率. 较低的VO2峰值水平 (≤80%的预测) 与这一老年人群的死亡风险增加有关.
科学领域:
- 老年学是一门学科.
- 心血管健康 呼吸系统健康
- 临床医学 临床医学
背景情况:
- 氧气吸收峰值 (VO2峰值) 是成年人的一个重要的健康指标.
- 它在80岁及以上的个体中的预后价值还未得到充分研究.
- 有限的研究存在于八十岁的VO2峰值和生存.
研究的目的:
- 评估VO2峰值对80岁及以上个体生存的预测能力.
- 为了研究VO2峰值和八十岁的死亡率之间的关联.
- 为了探索心肺健康的预后意义在最老的老年人中.
主要方法:
- 该研究包括来自单一中心的188名80岁以上的参与者.
- 用心肺运动测试来测量VO2峰值.
- 多变量考克斯回归模型根据%VO2峰值相对于预测值进行死亡风险评估,并根据年龄和中风进行调整.
主要成果:
- 22名参与者 (11.7%) 在随访期间死亡 (中位数为494天).
- 不幸存者年龄较大,VO2峰值较低,VO2峰值%较高.
- 在所有模型中,%VO2峰值≤80%与死亡率增加 (HR2.80-3.19,p<0.03) 有关.
结论:
- VO2峰值仍然是八十岁人的生存的一个重要预测指标.
- 这些发现强调了评估最年长人群的心肺健康的重要性.
- 结果为老龄化人口的医疗保健策略提供了信息.
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