在生物膜感染期间,由粒细胞髓衍生的抑制细胞活动是由糖解/HIF1a轴调节的

Christopher M Horn1, Prabhakar Arumugam1, Zachary Van Roy1

  • 1Department of Pathology, Microbiology, and Immunology and.

概括

黄金葡萄球菌假肢关节感染 (PJI) 涉及到促进炎症的骨髓性衍生抑制细胞 (MDSC). 针对他们的新陈代谢,特别是糖解和缺氧反应,在PJI小鼠模型中减少了细菌负担.

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