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Updated: Jul 2, 2025

Methods for Evaluating the Role of c-Fos and Dusp1 in Oncogene Dependence
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达布拉芬尼通过激活GCN2改变了MDSC的分化和功能

M Teresa Ciudad1,2, Rene Quevedo1,2, Sara Lamorte1,2

  • 1Tumor Immunotherapy Program, Princess Margaret Cancer Centre, University Health Network, Toronto, Canada.

Cancer research communications
|February 29, 2024
PubMed
概括

达布拉菲尼布是一种BRAF抑制剂,通过激活GCN2激酶,可以减少髓质衍生抑制细胞 (MDSCs). 这影响了MDSC的发展和功能,为癌症治疗提供了新的治疗策略.

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