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Updated: Jun 17, 2026

Functional Evaluation of Biological Neurotoxins in Networked Cultures of Stem Cell-derived Central Nervous System Neurons
15:05

Functional Evaluation of Biological Neurotoxins in Networked Cultures of Stem Cell-derived Central Nervous System Neurons

Published on: February 5, 2015

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全基因组病例对照研究中枢神经系统中因抗菌药物而产生的毒性

Joel Ås1, Ilma Bertulyte1, Nina Norgren2

  • 1Department of Medical Sciences, Clinical Pharmacogenomics and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.

PloS one
|February 29, 2024
PubMed
概括

LCP1,RETSAT和SFMBT2的遗传变异与抗菌药物对中枢神经系统 (CNS) 的毒性有关. 这项研究没有发现与血脑屏障载体的相关性,但确定了特定的不常见基因变异,这些变异有助于药物不良反应.

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Published on: February 22, 2015

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A Computerized Test Battery to Study Pharmacodynamic Effects on the Central Nervous System of Cholinergic Drugs in Early Phase Drug Development07:02

A Computerized Test Battery to Study Pharmacodynamic Effects on the Central Nervous System of Cholinergic Drugs in Early Phase Drug Development

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