视网膜方向选择性进化中的新转折
Takeshi Yoshimatsu1, Tom Baden2
1Department of the Ophthalmology and Visual Sciences, Washington University in St. Louis School of Medicine, St. Louis, Missouri, United States of America.
PLoS biology
|February 29, 2024
概括
在斑马鱼中发现了对哺乳动物运动视觉至关重要的星爆亚马克林细胞. 这些神经元与类似的星爆细胞一起被确定,但没有显示出强烈的运动选择性.
科学领域:
- 神经科学是一个神经科学.
- 视觉科学 视觉科学 视觉科学
- 比较生物学的比较生物学
背景情况:
- 星爆亚马克林细胞 (SAC) 是哺乳动物中关键的视网膜内神经元,对于处理运动信息至关重要.
- 它们在鱼类等非哺乳动物脊椎动物中的存在和功能在很大程度上仍未被探索.
研究的目的:
- 研究斑马鱼中星爆亚马克林细胞的存在和特征.
- 为了确定斑马鱼中的这些细胞是否表现出运动选择性,类似于它们的哺乳动物对应物.
主要方法:
- 免疫组织化学使用特定的标记物用于星爆亚马克林细胞.
- 视网膜整体安装制剂和共聚焦显微镜.
- 神经元形态和分布的分析.
主要成果:
- 这项研究确定了斑马鱼视网膜中的星爆亚马克林细胞.
- 还发现了第二个不同的星爆类神经元群体.
- 既没有发现的SAC,也没有发现类似星爆的神经元对运动方向表现出强烈的选择性.
结论:
- 星爆亚马克林细胞保留在斑马鱼中,这表明它们在脊椎动物视力中起着根本作用.
- 斑马鱼SAC中缺乏强烈的运动选择性表明,与哺乳动物相比,运动处理电路的演变不同.
相关概念视频
The Retina
69.1K
The retina is a layer of nervous tissue at the back of the eye that transduces light into neural signals. This process, called phototransduction, is carried out by rod and cone photoreceptor cells in the back of the retina.
69.1K
Anatomy of the Eyeball
7.1K
The eye is a spherical, hollow structure composed of three tissue layers. The outer layer — the fibrous tunic, comprises the sclera — a white structure — and the cornea, which is transparent. The sclera encompasses some of the ocular surface, most of which is not visible. However, the 'white of the eye' is distinctively visible in humans compared to other species. The cornea, a clear covering at the front of the eye, enables light penetration. The eye's middle...
7.1K
Photoreceptors and Visual Pathways
6.0K
At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...
6.0K
Vision
53.3K
Vision is the result of light being detected and transduced into neural signals by the retina of the eye. This information is then further analyzed and interpreted by the brain. First, light enters the front of the eye and is focused by the cornea and lens onto the retina—a thin sheet of neural tissue lining the back of the eye. Because of refraction through the convex lens of the eye, images are projected onto the retina upside-down and reversed.
53.3K
Color Vision
573
Color perception begins in the retina, the light-sensitive layer at the back of the eye. Two main theories explain how colors are seen: the trichromatic theory and the opponent-process theory. The trichromatic theory, proposed by Thomas Young in 1802 and extended by Hermann von Helmholtz in 1852, suggests that color vision is based on three types of cone receptors in the retina. These cones are sensitive to different but overlapping ranges of wavelengths corresponding to red, blue, and green.
573


