在计算机断层扫描上测量视神经外直径,以区分短暂缺血性发作
Rasime Pelin Kavak1, Nezih Kavak2, Senem Koca2
1Etlik City Hospital, Department of Radiology - Ankara, Turkey.
Revista da Associacao Medica Brasileira (1992)
|February 29, 2024
概括
平均光神经外直径可以帮助区分短暂性缺血性攻击 (TIA) 和中风患者. 与对照组相比,在中风和TIA组中观察到更高的视神经外直径测量.
科学领域:
- 神经学 神经学
- 眼科医生 眼科 眼科
- 放射学 放射学是一门学科.
背景情况:
- 过渡性缺血性攻击 (TIA) 和急性缺血性中风 (AIS) 是关键的神经事件.
- 准确及时诊断对于有效的患者管理至关重要.
- 视神经外直径 (ONSD) 是内压力变化的潜在生物标志物.
研究的目的:
- 评估平均光神经外直径 (mONSD) 在区分对照对象,TIA患者和AIS患者的有用性.
- 评估mONSD在确定TIA的诊断性能.
主要方法:
- 对773名患者 (18岁及以上) 的计算机断层扫描 (CT) 扫描的回顾性分析.
- 在控制,TIA和AIS组中测量mONSD.
- 统计分析以比较跨组的mONSD并评估TIA的预测价值.
主要成果:
- 与对照组相比,mONSD在AIS和TIA组中显著更高 (p<0.001).
- 与TIA和对照组相比,AIS子组中的mONSD显著高于TIA和对照组 (p<0.001).
- mONSD显示了TIA的高预测能力 (AUC=0.913,灵敏度=94.8%,特异性=73.9%),最佳切线为4.72mm.
结论:
- mONSD是区分对照组,TIA和AIS患者组的一个有价值的工具.
- 与中风和对照组相比,mONSD测量在TIA患者中是中间的.
- mONSD在TIA和中风的诊断中显示出作为一种非侵入性生物标志物的前景.
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