小纤维神经病变中的认知,行为和心理现象:一个病例对照研究
A Telesca1, E Soldini2, G Devigili3
1Ph.D. Program in Neuroscience, School of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy; Neuroalgology Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.
概括
小纤维神经病变 (SFN) 患者表现出正常的认知能力,但经历了增加的焦虑和alexithymia. 疼痛强度与情绪,生活质量和应对策略相关,这表明有针对性的心理支持是有益的.
科学领域:
- 神经学 神经学
- 心理学 心理学 心理学
- 疼痛医学 医学 疼痛医学
背景情况:
- 小纤维神经病变 (SFN) 是一种慢性疼痛疾病,对患者造成重大负担.
- 虽然情绪障碍已知,但SFN患者的认知和行为概况仍未得到充分研究.
研究的目的:
- 研究小纤维神经病变 (SFN) 患者的认知和行为特征.
- 为了比较患有疼痛性外围神经病变 (PPN) 的SFN患者和健康的对照人群 (HC).
主要方法:
- 34名SFN患者,36名PNP患者和30名HC患者接受了认知,行为,心理,生活质量和个性评估.
- 使用了经过验证的问卷和神经性疼痛的临床测量.
- 进行了跨组和相关性分析,并对多次比较进行了校正.
主要成果:
- 与PPN和HC相比,SFN患者表现出更高的焦虑和alexithymia.
- 在这两组患者中,不适应的应对策略普遍存在,SFN患者表现出更高的疼痛接受度.
- 疼痛强度与情绪,生活质量和灾难性情绪以及适应不良应对策略相关.
结论:
- SFN患者具有正常的认知特征,但表现出行为特征,包括情绪障碍,alexithymia,不适应性应对和糟糕的QoL,可能与疼痛强度有关.
- 在SFN患者中,体化和无价感需要临床关注治疗方法.
- 在SFN患者中,高度接受疼痛为基于心理的干预提供了潜力.
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