神经甲状腺激素代谢将环境温度的季节性变化与神经内分泌生殖轴相结合
Deborah I Lutterschmidt1, Kalera Stratton1, Treven J Winters1
1Department of Biology, Portland State University, OR, United States.
Hormones and behavior
|February 29, 2024
概括
环境温度会影响下丘脑中的甲状腺激素代谢,影响季节性生殖节奏. 低温改变了二氧化酶的酶,影响了带蛇的激素水平和雄性求爱行为.
科学领域:
- 神经内分泌学神经内分泌学
- 环境生理学环境生理学
- 时间生物学 时间生物学
背景情况:
- 环境温度是影响许多生物体季节节律的关键因素.
- 甲状腺激素在代谢调节和发育中起着至关重要的作用.
- 下丘脑集成环境线索来调节生理过程.
研究的目的:
- 为了研究环境温度如何影响下丘脑内的甲状腺激素代谢.
- 通过神经内分泌路径确定温度是否影响季节性生殖时间.
- 评估代酶酶在调节温度对生殖轴的影响中的作用.
主要方法:
- 免疫组织化学用于分析红边带蛇的下丘脑和脑垂体中的甲状腺刺激激素 (TSH),二氧化酶2 (Dio2) 和二氧化酶3 (Dio3).
- 蛇被暴露在低温 (4°C或12°C) 中,持续时间不同 (8-16周),模拟冬季休眠状态.
- 免疫活性和细胞数量的变化被量化并与行为观察相关联.
主要成果:
- 低温休眠改变了下丘脑中的神酶免疫活性,以持续时间依赖的方式增加了Dio2并减少了Dio3.
- 在Dio2/3中发生的这些相互变化有利于在下丘脑中积累triiodothyronine.
- 滴定酶免疫活性的时间变化与男性求爱行为的改变一致,需要至少8周的寒冷暴露.
结论:
- 通过甲状腺激素代谢调节生殖轴的神经内分泌通路可以传递温度信息.
- 环境温度通过下丘脑甲状腺激素代谢的改变影响季节性生殖时间.
- 这些发现对了解环境线索如何调解脊椎动物的季节性适应反应具有广泛的意义.
关键词:
在化过程中,化求爱行为 求爱行为神化剂的使用方法这就是 GnRH.爬行动物 爬行动物 爬行动物季节性繁殖 季节性繁殖蛇蛇蛇是什么意思 蛇蛇是什么意思在 TSH 中,您可以使用甲状腺增生蛋白 (Thyrotropin) 是一种甲状腺增生蛋白.冬季休眠状态 冬季休眠状态更多相关视频
相关概念视频
Functions of Thyroid Hormones
2.7K
The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
2.7K
Regulation of Hormone Secretion
3.4K
Regulation of hormone secretion is a finely tuned orchestration driven by various types of stimuli, encompassing neural, humoral, and hormonal signals. Environmental cues instigate neural stimuli, where action potentials traverse nerve fibers to reach their designated targets. An illustrative scenario is the body's response to stress, wherein the sympathetic nervous system releases epinephrine from the adrenal glands, inducing the well-known 'fight or flight' reaction.
Humoral...
Humoral...
3.4K
Synthesis and Regulation of Thyroid Hormones
4.6K
Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
4.6K
Thermoregulation
984
The human body has a sophisticated thermoregulation system that employs negative feedback mechanisms to maintain an optimal core temperature. When the core temperature drops, peripheral and central thermoreceptors send signals to the hypothalamus, activating the heat-promoting center. This center triggers several responses aimed at increasing the core temperature. First, vasoconstriction reduces the flow of warm blood from internal organs to the skin so that the heat is not lost from the skin,...
984
An Overview of the Endocrine System
8.3K
The endocrine system, a complex network of glands, orchestrates physiological balance within the body through the production and secretion of hormones. These hormones are chemical messengers in intercellular communication, acting as conduits between the secretory cells and distant target sites. They traverse the circulatory system by being released into the extracellular fluid, and their impact is specific to cells possessing receptors for a particular hormone.
The endocrine system collaborates...
The endocrine system collaborates...
8.3K
Factors Affecting Body Temperature
4.1K
As a nurse, it is vital to understand the factors affecting body temperature to monitor variations and effectively evaluate deviations from regular.
Factors may include:
Factors may include:
4.1K


