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Updated: Jul 2, 2025

Live Images of GLUT4 Protein Trafficking in Mouse Primary Hypothalamic Neurons Using Deconvolution Microscopy
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高血糖水平通过NLRP3-IL/MAPK/NF-κB相关的炎症通路加速动脉样硬化

Hui Sun1, Xiaotian Ma2, Hong Ma3

  • 1National Key Laboratory for Innovation and Transformation of Luobing Theory, The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education, Chinese National Health Commission and Chinese Academy of Medical Sciences, Department of Cardiology, Qilu Hospital of Shandong University, Jinan, China; Department of Cardiology, Qilu Hospital (Qingdao), Cheeloo College of Medicine, Shandong University, Qingdao, China.

Biochemical and biophysical research communications
|February 29, 2024
PubMed
概括

高血糖水平激活NLRP3炎症酶,加速糖尿病中的动脉样硬化. 抑制NLRP3降低了炎症和改善了葡萄糖耐受性,揭示了糖尿病相关心血管疾病的关键机制.

关键词:
动脉样硬化是一种动脉样硬化.糖尿病是一种糖尿病.炎症性细胞因子是炎症性细胞因子.介质蛋白是介质蛋白中的一种.这就是MAPK/NF-κBB.在NLRP3中,NLRP3是NLRP3中的一个.

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