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Updated: Jul 2, 2025

Myeloid Innate Signaling Pathway Regulation by MALT1 Paracaspase Activity
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抑制MALT1抑制了抗原特异性T细胞的反应

Iliana K Kerzeli1, Aikaterini Nasi1, Erika Fletcher1

  • 1Department of Pharmacy, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.

Cellular immunology
|February 29, 2024
PubMed
概括

一种MALT1抑制剂在体外选择性地抑制了调节性T细胞 (Tregs),但在体内显示出有限的抗瘤作用. 需要进一步的研究来优化癌症免疫治疗中MALT1抑制策略.

关键词:
抑制MALT1的抑制作用监管T细胞是T调控细胞.对T细胞依赖的免疫监测监测

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