缺血性和出血性中风的种族差异:一个生态流行病学研究
Dong-Seon Kang1, Pil-Sung Yang2, Daehoon Kim1
1Division of Cardiology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.
Thrombosis and haemostasis
|February 29, 2024
概括
与白人相比,东亚人患中风的发生率明显高,尽管体重指数较低. 这些发现凸显了根据种族和地区制定量身定制的中风预防策略的需要.
科学领域:
- 流行病学 流行病学
- 公共卫生 公共卫生
- 心血管研究研究心血管研究
背景情况:
- 调查中风发病率的种族差异对于全球健康公平至关重要.
- 以前的研究表明,不同人群中心血管疾病风险存在差异.
研究的目的:
- 评估和比较东亚和高加索人群中风的发病率.
- 为了确定中风亚型和风险因素的潜在种族差异.
主要方法:
- 一项生态流行病学研究利用英国生物银行和韩国国家健康保险服务数据.
- 包括112,750名东亚人和210,995名高加索人,不包括先前存在疾病的个人.
- 主要结局定义为5年随访期间的缺血性和出血性中风的复合.
主要成果:
- 东亚人体质指数较低 (23.7比26.4公斤/平方米),但身体不活动率较高 (49.6%比10.7%).
- 东亚人对整体中风 (IRR:3.48),缺血性中风 (IRR:3.70) 和出血性中风 (IRR:3.20) 的5年发病率明显较高.
- 在东亚人中,与心房相关的中风的发病率也较高 (IRR:2.04).
结论:
- 对于中风发病率的种族差异是显著的,并且在所有中风亚型中都是一致的.
- 这些发现强调了为有效预防中风开发特定区域和种族意识的方法的必要性.
- 进一步研究导致这些差异的潜在生物和环境因素是有必要的.
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