在慢性气流限制中与自我报告和生理反应相关的心肺循环运动测试中的异常运动性呼吸困难
Magnus Ekström1, Pei Zhi Li2, Hayley Lewthwaite3
1Division of Respiratory Medicine, Allergology and Palliative Medicine, Department of Clinical Sciences Lund, Faculty of Medicine, Lund University, Lund, Sweden; Clinical Exercise and Respiratory Physiology Laboratory, Department of Kinesiology and Physical Education, Faculty of Education, McGill University, Montréal, QC, Canada.
慢性空气流量限制 (CAL) 的异常运动性呼吸困难与较差的健康结果有关. 心肺运动检测 (CPET) 可以识别这种异常,验证其临床意义.
科学领域:
- 肺部医学 肺部医学
- 心血管呼吸系统生理学
- 临床运动测试 临床运动测试
背景情况:
- 炼性呼吸困难是心肺呼吸系统疾病的一个关键症状.
- 了解慢性气流限制 (CAL) 中的喘息对于患者管理至关重要.
研究的目的:
- 调查心肺运动测试 (CPET) 期间分级喘息异常与患有CAL的个体患者报告的和生理结果之间的关系.
主要方法:
- 对330名患有CAL且接受CPET的参与者 (≥40岁) 的分析.
- 气喘强度 (Borg CR10尺度) 根据运动参数使用规范参考方程进行评估.
- 与肺功能,运动能力,症状负担,体力活动和生活质量相关的关联被评估.
主要成果:
- 26%的参与者有异常低的运动能力.
- 与运动指标相比,在18-26%的参与者中观察到异常高的呼吸困难.
- 异常喘息与肺功能恶化,运动能力降低,症状负担增加和生活质量降低相关.
结论:
- 使用CPET规范性参考方程对喘息的分级证明了构造的有效性.
- 在CAL中异常的努力性呼吸困难与不良的临床,生理和功能结果有关.
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