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塑圈中的隐藏威胁:生产碳酶的肠杆菌在河水中殖民微塑料

Isabel Silva¹, Marta Tacão², Isabel Henriques³

¹Department of Life Sciences, Centre for Functional Ecology, Associate Laboratory TERRA, Faculty of Sciences and Technology, University of Coimbra, 3000-456 Coimbra, Portugal; CESAM (Centre for Environmental and Marine Studies), University of Aveiro, 3810-193 Aveiro, Portugal.

The Science of the total environment

|February 29, 2024

概括

河流中的微塑料 (MP) 作为耐卡巴胺细菌的载体,特别是在废水处理厂排放后. 这些细菌携带危险的耐药基因,增加环境传播和潜在的健康风险.

科学领域:

环境科学环境科学
微生物学微生物学
公共卫生公共卫生

背景情况:

碳烯耐药性是全球主要的健康威胁.
微塑料 (MP) 是新兴的环境污染物.
众议员在扩散碳烯耐药性的作用是未知的.

研究的目的:

为了调查一条河里的国会议员身上抗卡巴胺细菌的殖民化.
为了确定废水处理厂 (WWTP) 排放对这个殖民地的影响.
描述这些细菌的抗生素耐药性和毒性.

主要方法:

MPs (PP,PE,PET混合物和单纯的PET) 在WWTP的上游和下游部署.
隔离和鉴定了耐卡巴胺的肠道细菌 (CRE).
为了表征,进行了表型测试和全基因组测序.

主要成果:

在WWTP下游,CRE在MP的丰度显著增加.
混合国会议员显示了比单独的PET更高的殖民化.
孤立的CRE菌株具有多药耐药性,携带碳酶基因 (blaKPC-3,blaGES-5),并表现出病毒性特征.

结论:

MPs作为耐卡巴胺细菌及其基因的重要载体.
由于WWTP的排放,使得CRE对国会议员的殖民增强.
这突出了国会议员作为水生环境中CRE传播的潜在驱动力.

关键词:

碳二烯的使用方法淡水淡水的水是什么微塑料是一种微塑料.优先考虑抗生素耐药性病原体整个基因组测序的测序

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