脂乙醇检测了急性和慢性胰腺炎患者隐藏的重度酒精使用情况
Nicole Wong1, Cihang Gu2, Dhiraj Yadav2
1Department of Medicine, Oregon Health and Science University, Portland, Oregon.
概括
识别大量的酒精使用对于治疗胰腺炎至关重要,因为滥用正在增加,难以检测. 对酒精问题的早期干预可以减少胰腺炎的并发症.
科学领域:
- 胃肠病学 胃肠病学
- 成 药物 药物 药物 药物
- 公共卫生 公共卫生
背景情况:
- 胰腺炎的治疗选择有限,需要专注于可修改的风险因素,如大量饮酒.
- 滥用酒精和相关疾病的数量有所增加,特别是自COVID-19大流行以来.
- 从1961年至2016年,酒精相关胰腺炎的发病率每年增加约3%,复发是复发和慢性胰腺炎的关键风险因素.
研究的目的:
- 突出早期识别和干预滥用酒精在治疗胰腺炎方面的重要性.
- 为了解决准确评估胰腺炎患者饮酒摄入量的挑战.
主要方法:
- 审查有关滥用酒精和胰腺炎的当前趋势和文献.
- 讨论酒精消费现有诊断方法的局限性 (血液中的乙醇,尿液中的乙基葡萄化物,自我报告).
主要成果:
- 滥用酒精是胰腺炎的重要和日益增长的危险因素.
- 标准的酒精检测生物标志物可能是不可靠的,因为快速清除和潜在的患者戒酒之前的测试.
- 患者自我报告往往低估了酒精摄入量,可能会误导临床医生.
结论:
- 早期识别滥用酒精对于减轻胰腺炎发病率至关重要.
- 目前在临床环境中评估酒精消耗的方法不足以准确诊断胰腺炎患者.
- 需要进一步研究可靠的方法来检测这一群体的滥用酒精是合理的.
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