发表的核心成果的表现将实践指导方针变成实践指导方针
Sarah Rhodes1, Susanna Dodd2, Stefanie Deckert3
1Centre for Biostatistics, The University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.
Journal of clinical epidemiology
|February 29, 2024
概括
核心结果集 (COS) 在临床实践指南开发中并不经常使用. 指南结果与COS之间的一致性有限,表明需要探索COS实施的障碍.
科学领域:
- 医疗保健服务研究 医疗服务研究
- 临床实践指南 临床实践指南
- 结果测量 结果测量
背景情况:
- 核心成果集 (COS) 标准化了基本的健康结果,以提供一致的报告.
- 虽然COS对于决策者来说是有价值的,但它们的整合到实践指南开发中仍然没有得到评估.
- 之前的研究评估了试验和监管指导中的COS采用,但没有评估指导方针的创建.
研究的目的:
- 调查核心成果在国际实践指南中所代表的程度.
- 评估COS在开发临床实践指南中的当前使用情况.
主要方法:
- 在多个国家搜索了与十个高质量的COS相关的临床指南.
- 匹配指南范围 (条件,人口,结果) 与COS.
- 计算了指南中引用COS的比例,以及COS域与指南PICO声明的一致性.
主要成果:
- 分析了38条指导方针,其中包括170个PICO声明.
- 没有指南明确提到或引用相关的COS.
- 准则所涵盖的核心结果的中位数比例为30%.
结论:
- 临床指南制定过程中,COS并不是常规的信息来源.
- 在指南中的结果与COS中的结果之间存在有限的一致性.
- 需要进一步的研究,以确定在指导方针制定中实施COS的障碍和促进因素.
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