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Updated: Jul 1, 2025

Visualizing Mitophagy with Fluorescent Dyes for Mitochondria and Lysosome
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FBXL4:通过抑制线粒体吸食,防止线粒体枯竭

Prajakta Kulkarni1, Giang Thanh Nguyen-Dien1,2, Keri-Lyn Kozul1

  • 1Faculty of Medicine, School of Biomedical Sciences, University of Queensland, Brisbane, QLD, Australia.

Autophagy
|February 29, 2024
PubMed
概括

SCF-FBXL4 E3 泛基因酶通过降解BNIP3L和BNIP3受体来抑制线粒细胞衰变. FBXL4中的突变破坏了这种调节,导致线粒体功能障碍和MTDPS13中的枯竭.

关键词:
在BNIP3中,BNIP3是BNP3.在BNIP3L/NIX中使用.在FBXL4上.在 MTDPS13 中.线粒细胞衰变 (mitophagy) 是一种神经衰变的过程.无处不在的合酶

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