在接受脏瘤手术的患者中,囊素C基萨尔科佩尼亚指数的值
Shugo Yajima1, Yasukazu Nakanishi1, Ryo Andy Ogasawara1
1National Cancer Center Hospital East, Department of Urology, Chiba, Japan.
Clinical genitourinary cancer
|February 29, 2024
概括
在肌肉质量低的患者中,肉类症指数 (SI) 可能会高估功能 (eGFR). 低SI也与癌手术后更差的生存结果有关.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學.
- 老年病的医生 老年病的医生
- 在瘤学瘤学.
背景情况:
- 标志着肌肉强度和质量低下的萨尔科佩尼亚会影响身体表现.
- 石症指数 (SI) 由肌素和细胞素C水平得出的,与骨肌肉质量相关,可以查石症.
- 较低的SI表明肌肉质量较低,可能导致基于肌素的功能 (eGFR) 过度估计.
研究的目的:
- 在接受脏瘤手术的患者中,研究SI和估计的淋巴球过率 (eGFR) 之间的关联.
- 评估SI在预测术后结果的预后价值,包括整体存活率.
主要方法:
- 对322名接受脏瘤手术的患者进行了回顾性观察性研究.
- 使用计算机断层扫描来评估萨尔科佩尼亚,以测量psoas肌肉指数 (PMI),psoas肌肉密度 (PMD) 和骨肌肉面积 (SMA).
- 分析了SI,eGFR (手术前和后) 和术后结果之间的关联.
主要成果:
- 在男性和女性中,SI与骨肌面积 (SMA) 有中度的相关性.
- 根性切除术后,高SI患者的eGFR (98%) 与低SI患者 (69%) 相比下降更大.
- 发现低SI是预后不佳的预测因素.
结论:
- 临床医生应考虑低SI患者高估eGFR的可能性,尤其是在手术前后.
- 低SI可以作为一个有用的指标来预测这个患者群体的不良预后.
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