肺体积减小手术后的存活率:来自英国肺体积减小 (UKLVR) 注册表的结果
S C Buttery1,2, A Lewis3, A Alzetani4
1National Heart and Lung Institute, Imperial College, London, UK s.buttery@rbht.nhs.uk.
BMJ open respiratory research
|February 29, 2024
概括
肺体积减小手术 (LVRS) 和内支气管 (EBV) 放置为肺患者提供类似的长期存活率. UKLVR注册表显示,这些肺体积减小手术在疾病严重程度相似的患者身上进行.
科学领域:
- 肺部病理学 肺部病理学
- 胸部外科手术 胸部外科手术
- 医疗器械 医疗器械
背景情况:
- 肺管理包括肺体积减小手术 (LVRS) 和内支气管 (EBV) 放置.
- 英国肺体积减小 (UKLVR) 注册表是为了监测 LVR 程序的质量标准和结果而建立的.
- 英国各地的专业中心参与该注册.
研究的目的:
- 评估英国LVRS和EBV程序的结果和质量标准.
- 为了比较患者选择,手术并发症和LVRS和EBV之间的存活率.
主要方法:
- 分析了2017年1月至2022年6月期间接受LVRS或EBV治疗的541名患者的数据.
- 包含到2023年2月的疾病严重程度,准则遵守,并发症和生存数据.
- 在手术和基于门的干预之间比较基线特征和结果.
主要成果:
- 在LVRS (n=244) 和EBV (n=219) 组中,基线疾病严重程度相似 (例如,FEV1 32.1%与31.2%).
- 与LVRS (12天) 相比,EBV的平均逗留时间 (4天) 显著较短 (p=0.01).
- 在LVRS和EBV组之间,生存率没有显著差异 (10.8%与9.7%的死亡率,调整后的HR1.10).
结论:
- 肺气的LVRS和EBV程序在患有类似疾病严重程度的患者身上进行.
- 在LVRS和EBV干预之间,长期生存结果是可比的.
- 英国LVR注册提供了有关英国LVR程序的宝贵数据.
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