阿纳普拉斯马卡普拉:一种新兴的,由传播的动物传染病原体
Kursat Altay1, Ufuk Erol2, Omer Faruk Sahin2
1Department of Parasitology, Faculty of Veterinary Medicine, Sivas Cumhuriyet University, Sivas, 58140, Türkiye. kaltay@cumhuriyet.edu.tr.
Veterinary research communications
|February 29, 2024
概括
安纳普拉斯玛卡普拉是一种由传播的细菌,在各大洲的动物和人类中发现. 本综述检查了它的宿主,流行率和遗传多样性,突出了两个不同的基因型.
科学领域:
- 兽医微生物学 兽医微生物学
- 动物传播疾病 动物传播疾病
- 分子流行病学分子流行病学
背景情况:
- 类 (Anaplasma) 包含传播的细菌,其中一些会导致动物性性质炎.
- 2012年在中国的山羊中发现了Anaplasma capra,随后在2015年在人类中发现了它.
- 在亚洲,欧洲和非洲,A. capra已被检测到在人类,家禽和野生动物以及虫中.
研究的目的:
- 为提供对Anaplasma capra.的全面审查.
- 评估A. capra.的历史,宿主,分子流行,病原性和遗传多样性.
- 评估目前对A. capra的动物感染重要性和动物致病性的理解.
主要方法:
- 使用 gltA 和 groEL 基因序列的遗传学分析.
- 对A. capra.现有研究的文献综述.
- 评估宿主-病原体关系和地理分布.
主要成果:
- 遗传学分析揭示了A. capra的两个不同的基因型:基因型-1和基因型-2.
- 人类分离的A. capra主要属于基因型-2.
- 基因型分布在地理上有所不同,基因型-1在欧洲发现,两种基因型在亚洲发现. 主体-基因型关系是复杂的.
- A. capra在人类中引起临床疾病,但其充分的动物感染潜力和动物的致病性需要进一步研究.
结论:
- 阿纳普拉斯玛布拉表现出显著的遗传多样性,有两个主要的基因型.
- 了解A. capra基因型的地理分布和宿主特异性流行率至关重要.
- 需要进一步的研究来阐明Anaplasma capra在各种宿主中的动物性意义和病原性.
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