为重症儿童开发个性化的非侵入性通风口罩:一项实验室研究
Rosemijne R W P Pigmans1,2, Rozalinde Klein-Blommert3, Monica C van Gestel3
1Pediatric Intensive Care Unit, Emma Children's Hospital, Amsterdam UMC, Location AMC, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands. r.r.pigmans@amsterdamumc.nl.
Intensive care medicine experimental
|February 29, 2024
概括
个性化的3D打印非侵入性通风 (NIV) 面具为具有独特面部结构的儿童提供了快速有效的解决方案. 这些定制面具在临床前试验中显示出可接受的空气泄漏和压力性能.
科学领域:
- 生物医学工程 生物医学工程
- 儿科呼吸系统护理 儿童呼吸系统护理
背景情况:
- 非侵入性通风 (NIV) 面具的装配对儿科患者来说是一个挑战,特别是那些有面异常的儿科患者.
- 个性化的NIV口罩可以提高儿童的治疗效率.
- 目前的定制方法耗时.
研究的目的:
- 为了评估由3D打印软材料制成的个性化口腔口罩的空气泄漏和表面压力性能.
- 评估定制儿科NIV口罩快速,半自动化生产过程的可行性.
主要方法:
- 三种类型的生物相容个性化口腔口罩 (,光聚合物树脂) 被3D打印.
- 面具在患有异常面部特征的儿科头部模型上进行了测试.
- 进行了儿科NIV临床前模拟,以测量空气泄漏和表面压力.
主要成果:
- 个性化口罩通过半自动化3D打印工艺在12小时内生产出来.
- 空气泄漏率低于30%,平均表面压力大多低于正常的毛细血管压力.
- 软光聚合物树脂面膜显示出轻微的性能优势.
结论:
- 这项概念验证研究证明了生产具有可接受性能的生物相容,个性化的儿科NIV口罩的可行性.
- 快速的,半自动化的生产过程适合创建定制的NIV口罩.
- 需要进一步的临床研究来确定为重症儿童提供个性化NIV口罩的价值.
相关概念视频
Mechanical Ventilation III: Noninvasive Ventilation
112
Noninvasive positive-pressure ventilation (NIPPV), continuous positive airway pressure (CPAP), and bilevel positive airway pressure (BiPAP) are essential methods in respiratory care. These ventilation techniques offer unique benefits for patients with various respiratory conditions, providing adequate support without requiring intubation. Let's explore how each method is crucial in improving patient outcomes and enhancing respiratory therapy.
Noninvasive Positive-Pressure Ventilation...
Noninvasive Positive-Pressure Ventilation...
112
Oxygen Delivering System II: Venturi Mask and Transtracheal Oxygen
571
Oxygen therapy is a pivotal aspect of medical care, particularly for patients with respiratory ailments. Two prominent oxygen-delivering systems include the Venturi mask and the transtracheal oxygen catheter.
Venturi Mask
The Venturi mask, named after the Venturi effect, is designed to deliver precise oxygen concentrations. It consists of a large tube with an oxygen inlet that narrows down, causing a pressure drop that pulls air in through adjustable side ports. The mask is a lightweight,...
Venturi Mask
The Venturi mask, named after the Venturi effect, is designed to deliver precise oxygen concentrations. It consists of a large tube with an oxygen inlet that narrows down, causing a pressure drop that pulls air in through adjustable side ports. The mask is a lightweight,...
571
Mechanical Ventilation II: Invasive Ventilation
133
Ventilators are essential medical equipment used to aid patients with respiratory difficulties. Their primary function is to assist or replace spontaneous breathing by providing mechanical ventilation. There are two general classes of mechanical ventilators: negative-pressure and positive-pressure ventilators.
Negative-Pressure Ventilators
Negative-pressure ventilators create a vacuum around the chest or body to draw air into the lungs, simulating breathing. This method does not require an...
Negative-Pressure Ventilators
Negative-pressure ventilators create a vacuum around the chest or body to draw air into the lungs, simulating breathing. This method does not require an...
133


