灵活的支气管透视吸入和高流量鼻氧试验试验 (BUFFALO协议试验试验)
Susan Humphreys1,2,3, Andreas Schibler4,5, Tara Williams6
1Department of Anaesthesia, Queensland Children's Hospital, South Brisbane, Queensland, Australia. susan.humphreys@uq.edu.au.
Pilot and feasibility studies
|February 29, 2024
概括
这项试点试验调查了在儿科麻醉期间使用高流量鼻氧 (HFNO) 进行灵活支气管镜检查. 该研究评估了HFNO在减少低氧化和儿童救援氧气需求方面的可行性.
科学领域:
- 儿科麻醉学 儿科麻醉学
- 呼吸系统医学 呼吸系统医学
- 临床试验 临床试验
背景情况:
- 低氧症在灵活支气管镜检查的麻醉期间影响约30%的儿童.
- 高流量鼻氧 (HFNO) 可能会延长安全的呼吸暂停时间,并有利于有呼吸道异常的儿童.
- 关于HFNO在灵活支气管镜镜检查期间预防低氧血症的有效性,证据有限.
研究的目的:
- 评估在麻醉期间使用HFNO用于灵活支气管镜的可行性.
- 为了确定HFNO是否减少了救援氧化和低氧化症的需要.
- 为了告知一个更大的多中心随机临床试验的设计.
主要方法:
- 布法罗试验是一项双中心,随机对照试点研究.
- 81名年龄大于37周至16岁的儿童接受了选择性支气管镜检查,随机分配给HFNO或标准护理.
- 结果包括招聘可行性,合规性,可接受性和数据收集完成.
主要成果:
- 这个部分不在所提供的摘要中.
结论:
- 这些发现将指导规划一个更大的多中心随机临床试验.
- 该研究将支持拟议的试验程序的可行性.
相关概念视频
Mechanical Ventilation III: Noninvasive Ventilation
112
Noninvasive positive-pressure ventilation (NIPPV), continuous positive airway pressure (CPAP), and bilevel positive airway pressure (BiPAP) are essential methods in respiratory care. These ventilation techniques offer unique benefits for patients with various respiratory conditions, providing adequate support without requiring intubation. Let's explore how each method is crucial in improving patient outcomes and enhancing respiratory therapy.
Noninvasive Positive-Pressure Ventilation...
Noninvasive Positive-Pressure Ventilation...
112
Endoscopic Studies I: Bronchoscopy and Thoracoscopy
194
Endoscopy is a non-surgical medical technique used to examine a person's internal organs and vessels. This lesson will focus on two types of endoscopic studies: bronchoscopy and thoracoscopy.
Bronchoscopy
Description
Bronchoscopy is a procedure that involves direct visualization of the larynx, trachea, and bronchi for diagnostic and therapeutic purposes. A flexible fiber optic or rigid bronchoscope is used to carry out the procedure. The fiber-optic bronchoscope is more frequently used due...
Bronchoscopy
Description
Bronchoscopy is a procedure that involves direct visualization of the larynx, trachea, and bronchi for diagnostic and therapeutic purposes. A flexible fiber optic or rigid bronchoscope is used to carry out the procedure. The fiber-optic bronchoscope is more frequently used due...
194
Administering Oxygen by Nasal Cannula
549
Oxygen therapy is critical to patient care, especially for those struggling with respiratory issues. This intervention increases the oxygen concentration in the lungs, enhancing the amount of oxygen transported to the body's tissues. One standard method of delivering supplemental oxygen is through a nasal cannula, a non-invasive device that provides low to medium oxygen concentrations.
Nasal Cannulas
A nasal cannula is a lightweight tube split into two prongs placed in the nostrils,...
Nasal Cannulas
A nasal cannula is a lightweight tube split into two prongs placed in the nostrils,...
549
Oxygen Delivering System II: Venturi Mask and Transtracheal Oxygen
571
Oxygen therapy is a pivotal aspect of medical care, particularly for patients with respiratory ailments. Two prominent oxygen-delivering systems include the Venturi mask and the transtracheal oxygen catheter.
Venturi Mask
The Venturi mask, named after the Venturi effect, is designed to deliver precise oxygen concentrations. It consists of a large tube with an oxygen inlet that narrows down, causing a pressure drop that pulls air in through adjustable side ports. The mask is a lightweight,...
Venturi Mask
The Venturi mask, named after the Venturi effect, is designed to deliver precise oxygen concentrations. It consists of a large tube with an oxygen inlet that narrows down, causing a pressure drop that pulls air in through adjustable side ports. The mask is a lightweight,...
571
Oxygen Delivering System I: Nasal Cannula and Face Mask
320
The human body requires oxygen to function, and when the natural process of respiration is hindered, external devices, including the following, are needed to help deliver this vital gas.
Nasal Cannula
A nasal cannula is a lightweight tube split at one end into two prongs and placed in the nostrils. It is typically used to deliver low to medium levels of oxygen.
Suggested flow rate: The suggested flow rate for a nasal cannula typically ranges between 1 and 6 L/min.
Oxygen percentage setting:...
Nasal Cannula
A nasal cannula is a lightweight tube split at one end into two prongs and placed in the nostrils. It is typically used to deliver low to medium levels of oxygen.
Suggested flow rate: The suggested flow rate for a nasal cannula typically ranges between 1 and 6 L/min.
Oxygen percentage setting:...
320


