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高风险患者的可触摸乳房发现:自我和临床乳房检查是否值得?
Leah H Portnow1, Donna D'Alessio1, Elizabeth A Morris1
1Memorial Sloan Kettering Cancer Center, Evelyn H. Lauder Breast Center, New York, NY.
高风险女性有明显的乳腺问题,恶性瘤发生率为6.7%. 图像检查是有价值的,在检测乳腺癌方面具有很高的负预测价值.
科学领域:
- 在瘤学瘤学.
- 放射学 放射学是一门学科.
- 乳房成像 乳房成像
背景情况:
- 高风险女性的明显乳腺发现需要彻底评估.
- 评估恶性瘤的发病率和成像效用对于这一群体至关重要.
研究的目的:
- 评估乳腺成像发现,活检率和恶性瘤检测在高风险女性的可触摸乳腺问题.
- 为了确定各种成像模式的诊断性能.
主要方法:
- 乳腺成像和高风险女性有明显发现的医疗记录的回顾性审查 (2010-2016).
- 分析了乳房影像,超声波 (美国) 和磁共振成像 (MRI) 的相关性.
- 活检率,恶性瘤率和积极预测值的计算.
主要成果:
- 分析了238名高风险女性的322个明显发现.
- 在6.7%的女性 (16/238) 中检测到恶性病变,活检的阳性预测值为16.8%.
- 超声波 (美国) 和MRI显示癌症的灵敏度为100%,而乳房镜有64.3%.
结论:
- 在高危女性中,有形发现的恶性瘤率为6.7%,这强调了成像检查的重要性.
- 乳房成像在这个群体中显示出高负预测值.
- 图像导向活检是 palpable 异常的标准.
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