牛油果和瓜卡莫尔的消费和结肠直肠癌风险:多民族队列研究
Feon W Cheng1, Song-Yi Park2, Christopher A Haiman3
1Avocado Nutrition Center, Hass Avocado Board, Mission Viejo, California, USA.
Nutrition and cancer
|March 1, 2024
概括
在美国的一项大型研究中,食用梨和瓜卡莫尔并没有显著影响结直肠癌风险. 需要进一步的研究来探索食纤维和植物营养素对抗癌症的保护作用.
科学领域:
- 营养流行病学 营养流行病学
- 胃肠病学 胃肠病学
- 在瘤学瘤学.
背景情况:
- 食纤维和植物营养素因其对结肠直肠癌的潜在保护作用而得到认可.
- 这些有益营养素的低消费在美国普遍存在.
- 梨是丰富的纤维和植物营养素来源,这表明它可能在预防癌症方面发挥作用.
研究的目的:
- 研究食用梨和瓜卡莫尔与患结直肠癌的风险之间的关联.
- 分析不同的人口和种族/种族群体之间的这种关系.
主要方法:
- 在多民族队列研究中采用了前性队列研究设计.
- 食物频率调查问卷评估了梨和瓜卡莫尔的摄入量,将参与者分为低,中等和高消费组.
- 结肠直肠癌发病率通过监测,流行病学和最终结果 (SEER) 计划癌症登记处进行了跟踪.
主要成果:
- 在对共变量进行调整后,没有观察到梨/瓜卡莫尔消费与整体结肠直肠癌风险之间的显著关联.
- 根据解剖学子部位 (右结肠,左结肠,直肠) 和种族/种族的子组分析也没有显示出任何显著的关联.
- 增加消费水平的趋势测试没有显示出结直肠癌风险的统计显著降低 (p趋势≥0.06).
结论:
- 这项大型前性队列研究发现,食用梨或瓜卡莫尔与结直肠癌风险之间没有显著联系.
- 这些发现表明,在研究的人群中,梨和瓜卡莫尔的摄入量似乎不会改变结肠直肠癌风险.
- 对特定的植物营养素和纤维来源进行进一步的研究可能是癌症预防策略的必要条件.
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