开发使用炎症风险评分预测中度和高级肝细胞癌与乙型肝炎病毒相关的Nomogram
Hongyao Chen1,2, Renyi Yang1,2, Xiaopeng Yu1
1Hunan Provincial Hospital of Integrated Traditional Chinese and Western, Cancer Research Institute of Hunan Academy of Traditional Chinese Medicine, Hunan Academy of Chinese Medicine, Hunan, China.
Balkan medical journal
|March 1, 2024
概括
炎症风险评分是乙型肝炎病毒相关肝细胞癌 (HCC) 的显著预后因素. 一个开发出来的名图有效地预测了HCC患者的生存结果.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 在瘤学瘤学.
- 炎症研究 炎症研究
背景情况:
- 肝细胞癌 (HCC) 炎症标志物的预后影响尚未完全理解.
- 乙型肝炎病毒 (HBV) 是全球HCC的主要原因.
研究的目的:
- 评估炎症风险评分和与HBV相关的HCC的预后之间的关系.
- 确定HBV相关HCC的独立预后因素.
- 开发一个可预测患者存活率的诺米克图.
主要方法:
- 对174名中度至晚期HBV相关HCC患者进行了回顾性队列研究.
- 根据炎症风险得分分层分为高风险和低风险组.
- 使用独立的预后因素开发和验证预后名ogram.
主要成果:
- 高风险和低风险组之间的中位生存时间显著差异.
- 炎症风险评分,α-fetoprotein,跨动脉化学栓塞和BCLC阶段被确定为独立的预后因素.
- 诺莫格拉姆显示出对2至4年生存预测的良好的区分能力.
结论:
- 炎症风险评分是HBV相关HCC的关键预后指标.
- 一种新型的诺米图提供了一个实用的工具,用于预测HBV相关的HCC患者的存活率.
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